The hospital and the antimicrobial resistance
Keywords:
microbial resistance, prophylaxis, control and preventionAbstract
An analysis of bacterial resistance analysis is made during the medicine development in past years, contextualizing the significance or appearance of multi-resistant organisms at the hospital emphasizing the more relevant factors in the phenomenon genesis and in the more significant features in its prevention. It is indicated the impact of a inappropriate use of antibiotic-therapy on the mortality, stressing on the costs and also it is expressed the main principles to be taking into account. According the authors’s criterion these principles as a basis of the fight against sepsis are the following: a rational use of antibiotics and a reliable microbiology. Some experiences are mentioned used in our hospital to combat the phenomenon of bacterial resistance.
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References
1. Ferguson J. Antibiotic prescribing: how can emergence of
antibiotic resistance be delayed? Aust Prescr 2004; 27:39-
42.
2. Editorial resistencia a los antimicrobianos una amenaza
mundial. Boletín de medicamentos esenciales OMS N 28
y 29 año 2000.
3. Bantar C, Famiglietti A, Goldberg M. Three-year
surveillance study of nosocomial bacterial resistance in
Argentina. Intern J Infect Dis 2000; 4: 85-90.
4. La farmacorresistencia amenaza con malograr los avances
de la Medicina. Comunicado de prensa OMS/41 junio 12,
2000.
5. Wenzel RP. The Antibiotic Pipeline — Challenges, Costs,
and Values. N Engl J Med 2004;351:523-526) (Spelberg
B. et al. Trends in antimicrobial drug development:
implications for the future. Clin Infect Dis 2004;38:1279-
1286.
6. Dupont H, Mentec H, Sollet JP, Bleichner G. Impact of
appropriateness of initial antibiotic therapy on the
outcome of ventilator-associated pneumonia. Intensive
Care Med 2001; 27: 355-362.
7. Inadequate Antimicrobial Treatment of Infections. A Risk
Factor for Hospital Mortality Among Critically Ill
Patients. Kollef M., Sherman G., Ward S., Fraser V. Chest.
1999;115:462-474.
8. Vallés J., Rello J., Ochagavía A., Garnacho J., Alcalá MA.
Community-Acquired Bloodstream Infection in Critically
Ill Adult Patients. Impact of Shock and Inappropriate
Antibiotic Therapy on Survival. Chest. 2003;123:1615-
1624.
9. Ibrahim, et al. The Influence of Inadequate Antimicrobial
Treatment of Bloodstream Infections on Patient Outcomes
in the ICU Setting. Chest. 2000;118:146-155.
10. Leibovici, et al. The benefit of appropriate empirical
antibiotic treatment in patients with bloodstream infection.
J Intern Med.1998;244:379–386
11. Luna CM., et al. Impact of BAL data on the therapy and
outcome of ventilator associated pneumonia. Chest 1997;
111: 676-685.
12. Alvarez-Lerma, et al. Modification of empiric antibiotic
treatment in patients with pneumonia Intensive Care
Med.1996;22:387–394
13. Rello J. et al. Epidemiology and Outcomes of Ventilator-
Associated Pneumonia in a Large US Database. Am J
Respir Crit Care Med 1997;156,196-200
14. Mac Arthur RD., Miller M., Albertson T., Panacek E.,
Johnson D.,Teoh L.,Barchuk W. Adequacy of Early
Empiric Antibiotic Treatment and Survival in Severe
Sepsis: Experience from the MONARCS Trial. Clin Infect
Dis 2004;38:284–288.
15. Gould D, Nurses’ hand decontamination practice: results
of a local study. J Hosp Infect 1994;28:15-30.
16. Larson E, Kretzer EK. Compliance with handwashing
and barrier precautions. J Hosp Infect 1995;30:88-106.
17. Slaughter S, A comparison of the effect of universal use of
gloves and gowns. Ann Intern Med 1996;3:360-365.
18. Watanakunakorn C. An observational study of hand
washing and infection control practices by healthcare
workers. Infect Control Hosp Epidemiol 1998;19:858-860.
19. Pittet D, Hugonnet S, Harbarth S, Mourouga P, Sauvan V,
Touveneau S, Perneger TV. Effectiveness of a hospitalwide
program to improve complicance with hand hygiene.
Infection control Program Lancet 2000; 356:1307-1312.
20. Casewell M, Phillips I. Hands as route of transmission for
Klebsiella species. Br Med J 1977; 2:1315-7. 6. Pittet D,
Hugonnet S, Harbarth S, et al. Br Med J 1977;2:1315.
21. Ojajarvi J. Effectiveness of hand washing and disinfection
methods in removing transient bacteria after patient
nursing. J Hyg (Camb) 1980;85:193-203.
22. Dukes MNG. Drug Utilization Studies. Methods and uses.
WHO regional Publications. European series No. 45.
Finlandia, 1993.
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