Characterization of Patients with Chronic Spontaneous Urticaria Reactive or not to Autologous Serum

Authors

Keywords:

atopy, urticaria activity, quality of life, autologous serum, chronic spontaneous urticaria.

Abstract

Introduction: A positive autologous serum test is associated with prolonged spontaneous chronic urticaria that responds poorly to routine therapy.

Objective: To characterize patients with chronic spontaneous urticaria reactive or not to autologous serum.

Methods: A cross-sectional descriptive study was carried out in the Allergology Department of the Clinical-Surgical Hospital “Hermanos Ameijeiras”, between July 2022 and August 2023, in 60 patients with spontaneous chronic urticaria, who consented to participate. The patients underwent intradermal test of autologous serum to form two groups (positive and negative). Descriptive statistical measures were used to summarize the information, absolute numbers and percentages.

Results: Women predominated (81.6 %), the age group 19-39 years (43.3 %), those who received treatment (70.0 %), never smokers and ex-smokers (35.0 %) and normopesos (50.0 %). Bronchial asthma was the most frequent atopy (13.3 %). Intense/severe urticaria activity prevailed (35.0 %) and little affectation of quality of life (56.7 %), with no differences between the two groups. No relevant relationship was found between these two variables.

Conclusions: The autologous serum test is considered a bedside clinical test that can detect the presence of autoimmunity in patients with spontaneous chronic urticaria.

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Author Biographies

Sergio José Sánchez Hernández, Hospital "Hermanos Ameijeiras"

Residente de 3er año de Alergología. HHA

Eglis Ceballos Rodríguez, Hospital "Hermanos Ameijeiras"

Especialista de 2do grado en Alergología. HHA

Juan Miguel Báez López, Hospital "Hermanos Ameijeiras"

Especialista de 2do grado en Alergología. HHA

Iglermys Figueroa García, Hospital "Hermanos Ameijeiras"

Especialista de 2do grado en Alergología. HHA

Susel Quesada Peña, Hospital "Hermanos Ameijeiras"

Especialista de 1er grado en Bioestadística. HHA

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Published

2024-11-22

How to Cite

1.
Sánchez Hernández SJ, Ceballos Rodríguez E, Báez López JM, Figueroa García I, Quesada Peña S. Characterization of Patients with Chronic Spontaneous Urticaria Reactive or not to Autologous Serum. Acta Médica [Internet]. 2024 Nov. 22 [cited 2025 Apr. 10];25. Available from: https://revactamedica.sld.cu/index.php/act/article/view/501

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