The Cuban National Child Cohort Study (CNCCS) 1973-2025. Background and Design of the sixth follow-up.

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Keywords:

cohort study, Non-communicable diseases, DOHaD

Abstract

The concept of Developmental Origins of Health and Disease (DOHaD) is now widely recognized. Cuba has a valuable database to analyze this phenomenon from the National Cuban Child Cohort Study (CNCCS, acronym in English) which included all those born in the country during the first week of March 1973 that were the product of simple pregnancies and survived beyond the first week (N = 4299), who were studied at birth, at 7 months and at 7, 11 and 17 years.

The objective of this article is to provide an overview of the CNCCS and describe the design to be used in the sixth follow-up of its participants, which will include all those who currently reside in Havana, the capital of the country (n = 600). Each participant will be asked to visit the “Hospital Hermanos Ameijeiras” to complete a questionnaire covering sociodemographic data, lifestyle, eating habits and current health conditions. In addition, a physical examination, anthropometric measurements, evaluation of body composition through bioimpedance, blood chemistry, electrocardiogram and carotid ultrasound will be performed. Information about the health of the descendants and parents of the participants will also be collected. These data will be correlated with those obtained at birth and during childhood and adolescence.

This research represents a unique opportunity to delve deeper into the patterns and mechanisms involved in DOHaD and to develop strategies aimed at improving the health of the Cuban population.

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Published

2024-12-27

How to Cite

1.
Esquivel M, Vera Y, Buchaca E, Lye S, Matthews SG, Rodríguez L, et al. The Cuban National Child Cohort Study (CNCCS) 1973-2025. Background and Design of the sixth follow-up. Acta Médica [Internet]. 2024 Dec. 27 [cited 2025 Feb. 23];25. Available from: https://revactamedica.sld.cu/index.php/act/article/view/579

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