Transfusional related acute lung injury. A case report.
Keywords:
transfusion,, transfusion-induced acute lung injuryAbstract
Introduction: Transfusion-associated acute lung injury (TRALI) is a rare entity, defined as an acute respiratory distress syndrome characterized by acute respiratory failure and noncardiogenic pulmonary edema. It usually manifests within 6 hours after a transfusion.
Objective: To describe the clinical and radiological characteristics of a patient diagnosed with transfusion-associated acute lung injury.
Method: A clinical case of a patient admitted to intensive care with a diagnosis of TRALI after transfusion is presented.
Clinical case: A 41-year-old male patient with a personal pathological history of bipolar disorder. He was admitted to the operating room, where he was diagnosed with a renal tumor, for which he underwent surgery, performing a nephrectomy. He was transferred to ICU-8 and after 48 hours he presented active bleeding through the drain and surgical wound, related to hemoperitoneum, so it was decided to operate on him a second time. Four hours after the transfusion, the patient began to show signs of polypnea, desaturation, tachycardia and hypotension, associated with fever and chills. Due to respiratory deterioration, he required endotracheal intubation and mechanical ventilation. After 72 hours, the patient showed clinical and blood gas improvement and was weaned from mechanical ventilation and subsequently transferred to the ward.
Conclusion: Transfusion-associated acute lung injury represents a severe threat to life and is one of the main causes of death related to blood transfusion.
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Copyright (c) 2025 Ginette Rivera Pérez, Héctor Pérez Assef, Lissett Mozo Morales
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