A Cuban classification proposal for studying the insulin resistance syndrome in dyslipidemic patients

Authors

  • Raúl Orlando Calderín Bouza Hospital Clínico Quirúrgico "Hermanos Ameijeiras"
  • Miguel Ángel Yanes Quesada Hospital Clínico Quirúrgico "Hermanos Ameijeiras"
  • Jorge Luis León Álvarez Hospital Clínico Quirúrgico "Hermanos Ameijeiras"
  • Jorge Bacallao Gallestey Hospital Clínico Quirúrgico "Hermanos Ameijeiras"
  • Marelis Yanes Quesada Centro de Atención al Diabético. La Habana
  • Rosa Jiménez Paneque Centro de Atención al Diabético. La Habana
  • José Emilio Fernández-Britto Rodríguez Centro de Investigación y Referencia de la Aterosclerosis de la Habana

Keywords:

ACUSIR, insulin resistance syndrome, insulin resistance

Abstract

Introduction: The insulin resistance syndrome describes a group of related clinical abnormalities that occur more commonly in subjects with insulin resistance and compensatory hyperinsulinemia.
Objective: To identify the sensitivity and specificity of the new diagnostic classification of insulin resistance syndrome, ACUSIR, to identify the frequency of insulin resistance and the insulin resistance syndrome in dyslipidemic patients.
Methods: Descriptive and cross-sectional study in 344 patients with dyslipidemia aged 15-85 years who repeatedly attended the internal medicine clinic of Hermanos Ameijeiras Hospital. Patients with primary dyslipidemia, alcoholism, drugs that alter insulin sensitivity, endocrinopathies, hepatopathies and nephropathies, stress, obstructive apnea, secondary hypertension were excluded. All patients underwent the oral glucose tolerance test (OGTT), fasting insulinemia, cholesterol, triglycerides, and high density lipoprotein-cholesterol. Waist-hip index, waist circumference, body mass index, blood pressure, and the HOMA index were measured. The IR criterion was the same as the HOMA index (? 2.6).
Results: The frequency of insulin resistance was high in dyslipidemic patients, 258 patients (75%). The ACUSIR classification has a high sensitivity (75%) and a high specificity (86%) to detect IR in dyslipidemic patients (p=0.000).
Conclusions: The ACUSIR classification has good sensitivity and specificity to identify insulin resistance in dyslipidemic patients. Insulin resistance is associated with dyslipidemia.

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Published

2025-02-15

How to Cite

1.
Calderín Bouza RO, Yanes Quesada M Ángel, León Álvarez JL, Bacallao Gallestey J, Yanes Quesada M, Jiménez Paneque R, et al. A Cuban classification proposal for studying the insulin resistance syndrome in dyslipidemic patients. Acta Médica [Internet]. 2025 Feb. 15 [cited 2025 Feb. 22];19(1). Available from: https://revactamedica.sld.cu/index.php/act/article/view/703

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