Multiple conditions in a 75 year-old woman

Authors

  • Cosme M. Cand Huerta Hospital Hermanos Ameijeiras
  • Carlos A. Domínguez Álvarez Hospital Hermanos Ameijeiras

Keywords:

hemophagocytic syndrome, immune deficiency

Abstract

A case of a 75 year-old woman is presented because she was admitted due to fever, visceromegaly, immune deficiency with pancytopenia and hypogammaglobulinemia associated with ancient figures of ferritin and lactic dehydrogenase. Hemophagocytic syndrome diagnostic criteria were applied. Literature review is performed.

Downloads

Download data is not yet available.

References

1. Tierney LM, Thabet A, Nishino H. Case Records of the Massachusetts General Hospital (Case 10-2011): A woman with fever, confusion, liver failure, anemia and thrombocytopenia. N Engl J Med. 2011;364:1259-70.

2. Henter JI, Elinder G, Ost A. Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Semin Oncol. 1991;18:29-33.

3. Janka G, Zur Stadt U. Familial and acquired hemophagocytic lympho - histiocytosis. Hematology Am Soc Hematol Educ Program. 2005:82-8.

4. Filipovich AH. Hemophagocytic lymphohistiocytosis (HLH) and related disorders. Hematology Am Soc Hematol Educ Program. 2009;17:127-31.

5. Berkun Y, Padeh H. Macrophage activation syndrome in juvenile idiopathic Arthritis. In: Shoenfeld Y, Cervera R, Gershwin ME. Diagnostic Criteria in Autoimmune Diseases. USA: Edit. Humana Press. 2008:21-4.

6. Deane S, Selmi C, Teuber SS, Gershwin ME. Macrophage activation syndrome in autoimmune disease. Int Arch Allergy Immunol. 2010;153:109-20.

7. Maakaroun NR, Moanna A, Jacob JT, Albrecht H. Viral infections associated with hemophagocytic syndrome. Rev Med Virol. 2010;20:93-105.

8. Uttenthal BJ, Layton DM, Vyse TJ, Schreiber BE. Clinical problem solving: The wolf at the door. N Engl J Med. 2012;366:2216-21.

9. Fisman DN. Hemophagocytic syndromes and infection. Emerg Infect Dis. 2000;6:601-8.

10. Freeman HR, Ramanan AV. Review of haemophagocytic lymphohistiocytosis. Arch Dis Child. 2011;96:688-93.

11. Shabbir M, Lucas J, Lazarchick J, Shirai K. Secondary hemophagocytic syndrome in adults: a case series of 18 patients in a single institution and review of literature. Hematol Oncol. 2011;29:100-6.

Published

2014-12-15

How to Cite

1.
Cand Huerta CM, Domínguez Álvarez CA. Multiple conditions in a 75 year-old woman. Acta Médica [Internet]. 2014 Dec. 15 [cited 2025 Jun. 6];15(2). Available from: https://revactamedica.sld.cu/index.php/act/article/view/873

Issue

Section

Presentación de caso