Werner syndrome. Probable case report
Keywords:
Werner syndrome, progeria adult, malignant tumorsAbstract
Introduction
The Werner syndrome (WS) is a rare disease, autosomal recessive, which is characterized by signs of premature aging and tendency to develop malignant tumors. The objective of this article is to describe the clinical case of a patient with probable WS.
Clinical case presentation:A 34-year-old woman with a history of diabetes mellitus type II, mixed dyslipidemia, polycystic ovary syndrome and infertility. Who presents multiple lentiginous skin lesions of generalized distribution, important photodamage and non-melanocytic malignant tumors, in addition to physically dismorphic findings not consistent with her age.
According to the clinic, diagnostic tests and multidisciplinary study, the diagnosis of probable WS was proposed. Surgical treatment of skin lesions was initiated, with good therapeutic response.
Conclusion: WS is a rare but debilitating disorder that requires a comprehensive, multidisciplinary approach to management. While clinical symptoms can be difficult to diagnose due to their similarity to other conditions, early detection and appropriate treatment can significantly improve the prognosis for affected individuals.
Keywords: Werner syndrome, progeria adult, malignant tumors
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References
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Copyright (c) 2025 Lina María Marroquín Bravo, Ayda Mongui Fonseca , Elisa Ortuzar Menesia , Andry Devia-Pardo
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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